Andarine: S4
Andarine, better known as S4 is a selective androgen receptor modulator (SARM).
This SARM was developed by GTX Inc. Its main purpose was to be used in treatment against muscle wasting diseases.
SARMs have a different pathway than most performance-enhancers. When we look at Andarine, it has unique properties compared to most compounds.
One of the most effective and potent SARMs is Andarine, also referred to as the S4 SARM.
This SARM gets compared to steroidal compounds such as Winstrol and Anavar, mainly because it’s known to be as effective.
HOW DOES S4 ANDARINE WORK?
There is a reason SARMs are considered to be safer alternatives to steroids. Let me explain to you how SARMs like Andarine work.
A selective androgen receptor modulator (SARM) will directly bind to the androgen receptors in the body. Androgen receptors have important effects on the bones and muscles.
By binding to the receptors you will experience an increase in lean muscle mass and strength. Especially with the S4 SARM as it is much stronger than other SARMs.
Because Andarine does this in a selective way, there aren’t as much side effects as with steroids such as Winstrol.
Due to this SARM being anabolic it can give drastic results with very little side effects. Keep in mind that it isn’t completely side effect free.
WHAT TO EXPECT FROM THE S4 SARM
S4 is like a milder version of Winstrol. It’s really strong at low dosages of 25 to 50mg. Despite it being a quite mild SARM, it’s actually really strong.
You will see a lot of researchers stack Andarine with Ostarine to create a synergic effect. Especially during a caloric deficit, these two SARMs can help you hold onto your muscle mass.
The S4 SARM is used for pretty much everything. Cutting, bulking or re-comping is no issue with this selective androgen receptor modulator.
In a cut, you can definitely expect it to help you tight and vascular. It’s known to increase strength and mass even though you are consuming fewer calories.
And the great thing is that this SARM is considered being a clean compound. You won’t be having any water retention or bloat during a cut or a lean bulk.
It definitely belongs to one of the more powerful SARMs. I have no doubt in my mind that it is perhaps just as strong as LGD-4033.
HOW TO DOSE:
Andarine can be run solo or stacked with other SARMs.
If you do insist on stacking this compound for your research on rats, it’s suggested to stack with a few different options. S4 can be stacked well with LGD-4033, RAD-140, MK2866 & MK-677
A great womens stack is S4 & MK2866 which work great in a stack over 8 weeks.
As I mentioned, this SARM is effective at low dosages. Even at 25mg, you can experience muscle building effects. I don’t know a lot of compounds that are as effective as S4.
Most researchers will suggest starting with 25mg. From here on, you can gradually build up the dose to 50mg. You should not exceed this dosage because it is more than enough.
A typical Andarine cycle will usually last about 8 weeks. Don’t use this SARM for any longer.
Andarine needs to be dosed multiple times per day as it has a short half-life. – 2 x Per day is sufficient
My advice would be to stay within the recommended dosage of 25 to 50mg. Anecdotal experiences tell us that this is considered to be the sweet spot for most researchers.
SIDE EFFECTS:
Andarine does seem to have a few mild side effects. Don’t believe the people who say SARMs are completely side effect free because it isn’t true.
With that said, the side effects of Andarine are very mild. They are nothing if you compare them to the side effects of a steroidal compound like Testosterone or Trenbolone.
There are three potential side effects researchers can expect.
The first one is a light suppression of natural testosterone. This one doesn’t seem to be as common but it is important to mention. Because of Andarine’s high anabolic activity, you could potentially be suppressed during a cycle.
This is nothing to worry about as most users will recover perfectly fine. But some might require a post cycle therapy (PCT) in order to help them bounce back.
The second is a yellow tint to the vision. Andarine might cause a yellowish tint to the vision, usually at higher doses. This side effect will disappear after discontinuing the S4 SARM.
The side effects don’t happen to everybody. I just want to warn for researching purposes because there is a lot of misinformation about this SARM.
The third side effect is more prevalent at high dosages and could result in your eyes taking longer to adjust when going from areas that are dark to well-lit rooms and vice versa. This all subsides after completing use.






